O-Desmethyl Metoprolol

Names

[ CAS No. ]:
62572-94-5

[ Name ]:
O-Desmethyl Metoprolol

[Synonym ]:
1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol

Chemical & Physical Properties

[ Density]:
1.085g/cm3

[ Boiling Point ]:
424.6ºC at 760 mmHg

[ Melting Point ]:
70-72ºC

[ Molecular Formula ]:
C₁₄H₂₃NO₃

[ Molecular Weight ]:
253.33700

[ Flash Point ]:
210.6ºC

[ Exact Mass ]:
253.16800

[ PSA ]:
61.72000

[ LogP ]:
1.35000

[ Index of Refraction ]:
1.531

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA0512150

CHEMICAL NAME :: Benzeneethanol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-

CAS REGISTRY NUMBER :: 62572-94-5

LAST UPDATED :: 198809

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H23-N-O3

MOLECULAR WEIGHT :: 253.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,186,1979

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DA0512150

Articles

Identification of transformation products from β-blocking agents formed in wetland microcosms using LC-Q-ToF.

J. Mass Spectrom. 51 , 207-18, (2016)

Identification of degradation products from trace organic compounds, which may retain the biological activity of the parent compound, is an important step in understanding the long-term effects of the...