AZ10606120 dihydrochloride
Modify Date: 2025-08-25 18:17:59
AZ10606120 dihydrochloride structure
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Common Name | AZ10606120 dihydrochloride | ||
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| CAS Number | 607378-18-7 | Molecular Weight | 495.485 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H36Cl2N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AZ10606120 dihydrochlorideAZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth[1]. |
| Name | N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride,AZ 10606120 dihydrochloride |
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| Synonym | More Synonyms |
| Description | AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth[1]. |
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| Related Catalog | |
| Target |
IC50: ~10 nM (P2X7R)[1] |
| References |
| Molecular Formula | C25H36Cl2N4O2 |
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| Molecular Weight | 495.485 |
| Exact Mass | 494.221527 |
| InChIKey | BVFONFUUWORSPO-UHFFFAOYSA-N |
| SMILES | Cl.Cl.O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cccc2nc(NCCNCCO)ccc12 |
| 2-(Adamantan-1-yl)-N-[2-({2-[(2-hydroxyethyl)amino]ethyl}amino)quinolin-5-yl]acetamide dihydrochloride |
| 2-(Adamantan-1-yl)-N-[2-({2-[(2-hydroxyethyl)amino]ethyl}amino)-5-quinolinyl]acetamide dihydrochloride |
| Tricyclo[3.3.1.1]decane-1-acetamide, N-[2-[[2-[(2-hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-, hydrochloride (1:2) |