Bis-PEG1-acid
Modify Date: 2024-01-02 17:32:32
Bis-PEG1-acid structure
|
Common Name | Bis-PEG1-acid | ||
|---|---|---|---|---|
| CAS Number | 5961-83-1 | Molecular Weight | 162.14100 | |
| Density | 1.316g/cm3 | Boiling Point | 371.4ºC at 760 mmHg | |
| Molecular Formula | C6H10O5 | Melting Point | 60-61°C(lit.) | |
| MSDS | N/A | Flash Point | 158.7ºC | |
Use of Bis-PEG1-acidBis-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
| Name | 3-(2-carboxyethoxy)propanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Bis-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.316g/cm3 |
|---|---|
| Boiling Point | 371.4ºC at 760 mmHg |
| Melting Point | 60-61°C(lit.) |
| Molecular Formula | C6H10O5 |
| Molecular Weight | 162.14100 |
| Flash Point | 158.7ºC |
| Exact Mass | 162.05300 |
| PSA | 83.83000 |
| Index of Refraction | 1.475 |
| Hazard Codes | C |
|---|
|
~4%
Bis-PEG1-acid CAS#:5961-83-1 |
| Literature: CARGILL INCORPORATED Patent: WO2004/76398 A1, 2004 ; Location in patent: Page 8 ; |
|
~90%
Bis-PEG1-acid CAS#:5961-83-1 |
| Literature: Landeros, Jose M.; Silvestre, Hugo A.; Guadarrama, Patricia Journal of Molecular Structure, 2013 , vol. 1037, p. 412 - 419 |
|
~92%
Bis-PEG1-acid CAS#:5961-83-1 |
| Literature: Buchanan; Driega; Yap Canadian Journal of Chemistry, 2000 , vol. 78, # 3 p. 316 - 321 |
|
~%
Bis-PEG1-acid CAS#:5961-83-1 |
| Literature: Eastman Kodak Co. Patent: US2466419 , 1948 ; |
|
~%
Bis-PEG1-acid CAS#:5961-83-1 |
| Literature: Eastman Kodak Co. Patent: US2466419 , 1949 ; |
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