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2086689-02-1

2086689-02-1 structure
2086689-02-1 structure
  • Name: 2-(Biotin-amido)-1,3-bis(carboxylethoxy)propane
  • Chemical Name: 2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)
  • CAS Number: 2086689-02-1
  • Molecular Formula: C19H31N3O8S
  • Molecular Weight: 461.53
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:37:41
  • Modify Date: 2024-01-02 13:12:16
  • 2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)
Synonyms MFCD30723274
Description 2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H31N3O8S
Molecular Weight 461.53