Bis-PEG1-PFP ester

Modify Date: 2024-02-04 19:51:11

Bis-PEG1-PFP ester Structure
Bis-PEG1-PFP ester structure
Common Name Bis-PEG1-PFP ester
CAS Number 1807539-02-1 Molecular Weight 494.237
Density 1.6±0.1 g/cm3 Boiling Point 452.6±45.0 °C at 760 mmHg
Molecular Formula C18H8F10O5 Melting Point N/A
MSDS N/A Flash Point 219.4±23.6 °C

 Use of Bis-PEG1-PFP ester


Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Bis-PEG1-PFP ester
Synonym More Synonyms

 Bis-PEG1-PFP ester Biological Activity

Description Bis-PEG1-PFP ester is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. CORTEZ, Alex, et al. ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST. WO2017072662A1.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 452.6±45.0 °C at 760 mmHg
Molecular Formula C18H8F10O5
Molecular Weight 494.237
Flash Point 219.4±23.6 °C
Exact Mass 494.021210
LogP 4.99
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.460

 Synonyms

MFCD26127804
Propanoic acid, 3,3'-oxybis-, bis(2,3,4,5,6-pentafluorophenyl) ester
Bis(pentafluorophenyl) 3,3'-oxydipropanoate
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