1314378-12-5
1314378-12-5 structure
- Name: Bis-PEG4-PFP ester
- Chemical Name: Bis-PEG4-PFP ester
- CAS Number: 1314378-12-5
- Molecular Formula: C24H20F10O8
- Molecular Weight: 626.395
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-10-17 20:07:50
- Modify Date: 2024-01-10 13:34:11
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Bis-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Bis-PEG4-PFP ester |
|---|---|
| Synonyms |
Bis(pentafluorophenyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate
MFCD21363293 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, bis(2,3,4,5,6-pentafluorophenyl) ester |
| Description | Bis-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 570.5±50.0 °C at 760 mmHg |
| Molecular Formula | C24H20F10O8 |
| Molecular Weight | 626.395 |
| Flash Point | 287.7±25.0 °C |
| Exact Mass | 626.099854 |
| LogP | 3.92 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.463 |