Integrin Antagonists 27

Modify Date: 2024-01-06 17:03:54

Integrin Antagonists 27 Structure
Integrin Antagonists 27 structure
Common Name Integrin Antagonists 27
CAS Number 593274-97-6 Molecular Weight 444.44
Density N/A Boiling Point N/A
Molecular Formula C24H20N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Integrin Antagonists 27


Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. Target: Integrinin vitro: Integrin Antagonists 27 is treated with a panel of cancer cell-lines (breast cancer cell line MDA-MB-435, breast cancer cell lines MCF-7, mouse fibroblast NIH3T3, ovarian cancer cell line HEY, lung cancer cell line NCI-H1975) with all IC50 of >20 uM.

 Names

Name Integrin Antagonists 27

 Integrin Antagonists 27 Biological Activity

Description Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. Target: Integrinin vitro: Integrin Antagonists 27 is treated with a panel of cancer cell-lines (breast cancer cell line MDA-MB-435, breast cancer cell lines MCF-7, mouse fibroblast NIH3T3, ovarian cancer cell line HEY, lung cancer cell line NCI-H1975) with all IC50 of >20 uM.
Related Catalog
References

[1]. Dayam R, et al. Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents. J Med Chem. 2006 Jul 27;49(15):4526-4534.

 Chemical & Physical Properties

Molecular Formula C24H20N4O5
Molecular Weight 444.44
Storage condition 2-8℃
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