1628741-91-2

1628741-91-2 structure

Name: SSTR5 antagonists 1
Chemical Name: SSTR5 antagonists 1
CAS Number: 1628741-91-2
Molecular Formula: C₂₈H₃₄FN₃O₅
Molecular Weight: 511.59
Catalog: Signaling Pathways GPCR/G Protein Somatostatin Receptor
Create Date: 2019-03-31 04:44:33
Modify Date: 2024-01-09 11:09:50
SSTR5 antagonists 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)[1]

Name	SSTR5 antagonists 1

Description	SSTR5 antagonists 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)[1]
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor Research Areas >> Metabolic Disease
Target	IC50: 9.6 nM (hSSTR5), 57 nM (mSSTR5)[1]
References	[1]. Hirose H, et al. Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus. Bioorg Med Chem. 2017 Aug 1;25(15):4175-4193.

Molecular Formula	C₂₈H₃₄FN₃O₅
Molecular Weight	511.59