SSTR5 antagonists 1

Modify Date: 2024-01-09 11:09:50

SSTR5 antagonists 1 structure	Common Name	SSTR5 antagonists 1
	CAS Number	1628741-91-2	Molecular Weight	511.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₄FN₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SSTR5 antagonists 1

SSTR5 antagonists 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)[1]

Name	SSTR5 antagonists 1

Description	SSTR5 antagonists 1 is a potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. (Compound 25a)[1]
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor Research Areas >> Metabolic Disease
Target	IC50: 9.6 nM (hSSTR5), 57 nM (mSSTR5)[1]
References	[1]. Hirose H, et al. Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus. Bioorg Med Chem. 2017 Aug 1;25(15):4175-4193.

Molecular Formula	C₂₈H₃₄FN₃O₅
Molecular Weight	511.59