478963-79-0

478963-79-0 structure

Name: Calcium-Sensing Receptor Antagonists I
Chemical Name: 1-propan-2-yl-4-(4-propan-2-ylphenyl)-6-prop-2-ynoxyquinazolin-2-one
CAS Number: 478963-79-0
Molecular Formula: C₂₃H₂₄N₂O₂
Molecular Weight: 360.44900
Catalog: Signaling Pathways GPCR/G Protein CaSR
Create Date: 2018-12-03 09:36:33
Modify Date: 2025-08-25 21:28:39
Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors. IC50 value:Target: CaSRCalcium-Sensing Receptor Antagonists I is useful for osteoporosis and other bone conditions

Name	1-propan-2-yl-4-(4-propan-2-ylphenyl)-6-prop-2-ynoxyquinazolin-2-one
Synonyms	CS-0307 1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-2(1H)-QUINAZOLINONE Calcium-Sensing Receptor Antagonists I

Description	Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors. IC50 value:Target: CaSRCalcium-Sensing Receptor Antagonists I is useful for osteoporosis and other bone conditions
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CaSR Research Areas >> Others
References	[1]. Widler, Leo et al. 1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists.Journal of Medicinal Chemistry(2010),53(5), 2250-2263.