Licochalcone A

Modify Date: 2024-01-02 17:47:52

Licochalcone A structure	Common Name	Licochalcone A
	CAS Number	58749-22-7	Molecular Weight	338.397
	Density	1.2±0.1 g/cm3	Boiling Point	532.6±50.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₂O₄	Melting Point	100°
	MSDS	N/A	Flash Point	186.9±23.6 °C

Use of Licochalcone A

Licochalcone A, a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch, presents obvious anti-cancer effects. The IC50 value is 0.97 μM for UGT1A1.

Name	(E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
Synonym	More Synonyms

Description	Licochalcone A, a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch, presents obvious anti-cancer effects. The IC50 value is 0.97 μM for UGT1A1.
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Natural Products >> Flavonoids Research Areas >> Cancer
References	[1]. Tang ZH, et al. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Sci Rep. 2016 May 17;6:26241. [2]. Hong Xin, et al. Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. Food and Chemical ToxicologyVolume 90, April 2016, Pages 112–122 [3]. Egler J, et al. Licochalcone A Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2015;37(5):2060-70.

Description

Licochalcone A, a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch, presents obvious anti-cancer effects. The IC50 value is 0.97 μM for UGT1A1.

Related Catalog

Signaling Pathways >> Autophagy >> Autophagy

Natural Products >> Flavonoids

Research Areas >> Cancer

References

[1]. Tang ZH, et al. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Sci Rep. 2016 May 17;6:26241.

[2]. Hong Xin, et al. Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. Food and Chemical ToxicologyVolume 90, April 2016, Pages 112–122

[3]. Egler J, et al. Licochalcone A Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2015;37(5):2060-70.

Density	1.2±0.1 g/cm3
Boiling Point	532.6±50.0 °C at 760 mmHg
Melting Point	100°
Molecular Formula	C₂₁H₂₂O₄
Molecular Weight	338.397
Flash Point	186.9±23.6 °C
Exact Mass	338.151794
PSA	66.76000
LogP	4.95
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.611
Storage condition	?20°C

Hazard Codes	Xn
Risk Phrases	20/21/22
Safety Phrases	36/37
RTECS	UB8755000

(E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one

Licochalcone A

(2E)-3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hdyroxyphenyl)-2-propen-1-one

LicochalconeA

LICOAGROCHACONE A

(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one

2-Propen-1-one,3-(5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-,(E)

(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

Licochalcone-A,Synthetic

5-(1,1-dimethylallyl)-4,4'-dihydroxy-2-methoxychalcone

(2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one

3-Dimethylallyl-4,4'-dihydroxy-6-methoxychalcone

2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-

BioBioPha
China
Product Name: Licochalcone A
Price: ￥Inquiry/20mg
Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Licochalcone A
Price: ￥588.0/20mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Licochalcone A
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Licochalcone a
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Zhejiang Hangyu API Co., Ltd
China
Product Name: LICOCHALCONE-A
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: LICOCHALCONE-A
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Licochalcone A

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