UNII:6G5ELX5XYN
Modify Date: 2024-01-01 23:47:06
UNII:6G5ELX5XYN structure
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Common Name | UNII:6G5ELX5XYN | ||
|---|---|---|---|---|
| CAS Number | 5694-00-8 | Molecular Weight | 87.077 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 321.9±31.0 °C at 760 mmHg | |
| Molecular Formula | C3H5NO2 | Melting Point | 32-34ºC | |
| MSDS | Chinese USA | Flash Point | 240.8±21.2 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
Use of UNII:6G5ELX5XYNGlycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects[1]. |
| Name | Oxiranecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 321.9±31.0 °C at 760 mmHg |
| Melting Point | 32-34ºC |
| Molecular Formula | C3H5NO2 |
| Molecular Weight | 87.077 |
| Flash Point | 240.8±21.2 °C |
| Exact Mass | 87.032028 |
| PSA | 55.62000 |
| LogP | -2.21 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.516 |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H315-H317-H319-H335-H350 |
| Precautionary Statements | P201-P261-P280-P305 + P351 + P338-P308 + P313 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Phrases | 45-46-22-36/37/38-43 |
| Safety Phrases | 53-26-36/37-45 |
| RIDADR | NONH for all modes of transport |
| RTECS | MB3200000 |
| HS Code | 2924299090 |
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UNII:6G5ELX5XYN CAS#:5694-00-8 |
| Literature: Mansour Lakouraj; Bahrami Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 8 p. 974 - 975 |
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UNII:6G5ELX5XYN CAS#:5694-00-8 |
| Literature: Mutation Research - Genetic Toxicology and Environmental Mutagenesis, , vol. 535, # 1 p. 15 - 24 |
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UNII:6G5ELX5XYN CAS#:5694-00-8 |
| Literature: Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3202 - 3206 |
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UNII:6G5ELX5XYN CAS#:5694-00-8 |
| Literature: Helvetica Chimica Acta, , vol. 77, # 8 p. 2251 - 2285 |
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UNII:6G5ELX5XYN CAS#:5694-00-8 |
| Literature: Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3202 - 3206 |
CAS#:1079950-08-5![N-Acetyl-S-[2-amino-1-(hydroxyMethyl)-2-oxoethyl]-L-cysteine-1,1-dimethylethyl Ester structure](https://www.chemsrc.com/caspic/309/1079950-10-9.png)
CAS#:1079950-10-9| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure.
PLoS ONE 9(5) , e94904, (2014) Metabolism of xenobiotics by cytochrome P450s (encoded by the CYP genes) often leads to bio-activation, producing reactive metabolites that interfere with cellular processes and cause DNA damage. In t... |
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Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide.
Arch. Toxicol. 85(6) , 601-6, (2011) A dose of 0.99 mg d(3)-acrylamide (d(3)-AA) (13.2 μg/kg body weight) was ingested by a healthy male volunteer. Urine samples were collected over a period of 46 h after the intake and analyzed for the ... |
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Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide.
Mutat. Res. 752(1-2) , 1-7, (2013) Acrylamide (AA) is a probable human carcinogen generated in carbohydrate-rich foodstuffs upon heating. Glycidamide (GA), formed via epoxidation, presumably mediated by cytochrome P450 2E1, is consider... |
| 2-Oxiranecarboxamide |
| Oxirane-2-carboxamide |
| UNII:6G5ELX5XYN |