DC Chemicals Limited
China
Product Name: Glycidamide
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: oxirane-2-carboxamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

5694-00-8

5694-00-8 structure

Name: UNII:6G5ELX5XYN
Chemical Name: Oxiranecarboxamide
CAS Number: 5694-00-8
Molecular Formula: C₃H₅NO₂
Molecular Weight: 87.077
Catalog: analytical chemistry Standard Volatile Organic Compounds (VOCs)
Create Date: 2018-04-12 08:00:00
Modify Date: 2024-01-01 23:47:06
Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects[1].

Name	Oxiranecarboxamide
Synonyms	2-Oxiranecarboxamide Oxirane-2-carboxamide UNII:6G5ELX5XYN

Description	Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Besaratinia A, et al. Genotoxicity of acrylamide and glycidamide. J Natl Cancer Inst. 2004 Jul 7;96(13):1023-9.

Density	1.4±0.1 g/cm3
Boiling Point	321.9±31.0 °C at 760 mmHg
Melting Point	32-34ºC
Molecular Formula	C₃H₅NO₂
Molecular Weight	87.077
Flash Point	240.8±21.2 °C
Exact Mass	87.032028
PSA	55.62000
LogP	-2.21
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.516
Storage condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB3200000

CHEMICAL NAME :: Glycidamide

CAS REGISTRY NUMBER :: 5694-00-8

BEILSTEIN REFERENCE NO. :: 1280744

LAST UPDATED :: 199712

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C3-H5-N-O2

MOLECULAR WEIGHT :: 87.09

WISWESSER LINE NOTATION :: T3OTJ BVZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 800 mg/kg/8D-I

TOXIC EFFECTS :: Behavioral - alteration of operant conditioning Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 400 mg/kg

SEX/DURATION :: male 8 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 800 mg/kg

SEX/DURATION :: male 8 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 350 mg/kg

SEX/DURATION :: male 7 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: Unscheduled DNA synthesis

TYPE OF TEST :: Dominant lethal test

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,175,1996

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H302-H315-H317-H319-H335-H350
Precautionary Statements	P201-P261-P280-P305 + P351 + P338-P308 + P313
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T
Risk Phrases	45-46-22-36/37/38-43
Safety Phrases	53-26-36/37-45
RIDADR	NONH for all modes of transport
RTECS	MB3200000
HS Code	2924299090

107-13-1

~78%

5694-00-8

Literature: Mansour Lakouraj; Bahrami Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 8 p. 974 - 975

79-06-1

5694-00-8

Literature: Mutation Research - Genetic Toxicology and Environmental Mutagenesis, , vol. 535, # 1 p. 15 - 24

615-34-9

5694-00-8

Literature: Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3202 - 3206

4538-51-6

5694-00-8

Literature: Helvetica Chimica Acta, , vol. 77, # 8 p. 2251 - 2285

107-13-1

5694-00-8

54393-33-8

Literature: Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3202 - 3206

Precursor 4
107-13-1 79-06-1 615-34-9 4538-51-6
DownStream 2
1079950-08-5 1079950-10-9

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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