Selective conversion of nitriles to amides by Amberlyst A-26 supported hydroperoxide

MM Lakouraj, K Bahrami

Index: Mansour Lakouraj; Bahrami Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 8 p. 974 - 975

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Citation Number: 5

Abstract

Abstract: A mild, efficient and selective conversion of nitriles to amides is achieved by employing Amberlyst A-26 supported hydroperoxide, which is prepared in situ from hydrogen peroxide and Amberlyst A-26 (OH-form). Nitriles and dinitriles are transformed to their corresponding amides and diamides, respectively. Reactions proceed within 0.5-5 hr upon addition of a catalytic amount of Amberlyst A 26 (OH-) to a methanolic solution of ...