4-(4-chlorobenzyl)phthalazin-1-ol

Modify Date: 2025-08-22 13:41:37

4-(4-chlorobenzyl)phthalazin-1-ol Structure
4-(4-chlorobenzyl)phthalazin-1-ol structure
Common Name 4-(4-chlorobenzyl)phthalazin-1-ol
CAS Number 53242-88-9 Molecular Weight 270.714
Density 1.3±0.1 g/cm3 Boiling Point 522.3ºC at 760 mmHg
Molecular Formula C15H11ClN2O Melting Point N/A
MSDS N/A Flash Point 269.7ºC

 Names

Name 4-(4-Chlorobenzyl)phthalazin-1(2H)-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 522.3ºC at 760 mmHg
Molecular Formula C15H11ClN2O
Molecular Weight 270.714
Flash Point 269.7ºC
Exact Mass 270.056000
PSA 45.75000
LogP 3.09
Index of Refraction 1.661
InChIKey NLXGCQIEVZYDRS-UHFFFAOYSA-N
SMILES O=c1[nH]nc(Cc2ccc(Cl)cc2)c2ccccc12

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

~90%

4-(4-chlorobenzyl)phthalazin-1-ol Structure

4-(4-chlorobenz...

CAS#:53242-88-9

Literature: GLAXO GROUP LIMITED Patent: WO2007/122156 A1, 2007 ; Location in patent: Page/Page column 114-115 ; WO 2007/122156 A1

~77%

4-(4-chlorobenzyl)phthalazin-1-ol Structure

4-(4-chlorobenz...

CAS#:53242-88-9

Literature: Derita, Marcos; Del Olmo, Esther; Barboza, Bianca; Garcia-Cadenas, Ana Esther; Lopez-Perez, Jose Luis; Andujar, Sebastian; Enriz, Daniel; Zacchino, Susana; Feliciano, Arturo San Molecules, 2013 , vol. 18, # 3 p. 3479 - 3501

~67%

4-(4-chlorobenzyl)phthalazin-1-ol Structure

4-(4-chlorobenz...

CAS#:53242-88-9

Literature: Havaldar, Freddy H.; Dabholkar, Bhushan V.; Mule, Ganesh B. Synthetic Communications, 2013 , vol. 43, # 8 p. 1127 - 1137

~87%

4-(4-chlorobenzyl)phthalazin-1-ol Structure

4-(4-chlorobenz...

CAS#:53242-88-9

Literature: Scheffler; Engel; Kutscher; Sheldrick; Bell Archiv der Pharmazie, 1988 , vol. 321, # 4 p. 205 - 208

~%

4-(4-chlorobenzyl)phthalazin-1-ol Structure

4-(4-chlorobenz...

CAS#:53242-88-9

Literature: Archiv der Pharmazie, , vol. 321, # 4 p. 205 - 208

~%

4-(4-chlorobenzyl)phthalazin-1-ol Structure

4-(4-chlorobenz...

CAS#:53242-88-9

Literature: Synthetic Communications, , vol. 43, # 8 p. 1127 - 1137

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-[(4-Chlorophenyl)methyl]-1(2H)-phthalazinone
1(2H)-Phthalazinone, 4-[(4-chlorophenyl)methyl]-
4-(4-Chlorobenzyl)phthalazin-1(2H)-one
4-(4-Chlorobenzyl)-1(2H)-phthalazinone
Azelastine impurity D
4-(4-chlorobenzyl)phthalazin-1-ol
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