Quisqualic acid structure
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Common Name | Quisqualic acid | ||
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CAS Number | 52809-07-1 | Molecular Weight | 189.126 | |
Density | 2.0±0.1 g/cm3 | Boiling Point | 405.9±55.0 °C at 760 mmHg | |
Molecular Formula | C5H7N3O5 | Melting Point | 185-187ºC dec. | |
MSDS | Chinese USA | Flash Point | 199.3±31.5 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Quisqualic acidQuisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis chinensis[1][2]. |
Name | (+)-Quisqualic Acid |
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Synonym | More Synonyms |
Description | Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis chinensis[1][2]. |
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Related Catalog | |
Target |
mGluR1R:45 nM (EC50) mGluR1R:10 nM (Ki) mGluR2R:108 μM (IC50) mGluR2R:113 μM (Ki) mGluR4R:593 μM (IC50) mGluR4R:112 μM (Ki) |
In Vitro | Quisqualic acid is an agonist of AMPA and metabotropic glutamate receptors. Quisqualic acid activates mGluR2R (EC50=108 μM; Ki=113 μM) and mGluR4R (EC50=593 μM; Ki=112 μM)[1]. |
References |
Density | 2.0±0.1 g/cm3 |
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Boiling Point | 405.9±55.0 °C at 760 mmHg |
Melting Point | 185-187ºC dec. |
Molecular Formula | C5H7N3O5 |
Molecular Weight | 189.126 |
Flash Point | 199.3±31.5 °C |
Exact Mass | 189.038574 |
PSA | 131.32000 |
LogP | -1.85 |
Vapour Pressure | 0.0±2.1 mmHg at 25°C |
Index of Refraction | 1.726 |
~10% Quisqualic acid CAS#:52809-07-1 |
Literature: Murakoshi, Isamu; Ikegami, Fumio; Yoneda, Yoshihiro; Ihara, Harumi; Sakata, Kumiko; Koide, Chiharu Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1473 - 1478 |
~% Quisqualic acid CAS#:52809-07-1 |
Literature: Ikegami, Fumio; Takayama, Kyoko; Tajima, Chiho; Murakoshi, Isamu Phytochemistry (Elsevier), 1988 , vol. 27, # 7 p. 2011 - 2016 |
~% Quisqualic acid CAS#:52809-07-1 |
Literature: Baldwin, Jack E.; Adlington, Robert M.; Birch, David J. Journal of the Chemical Society, Chemical Communications, 1985 , # 5 p. 256 - 257 |
~% Quisqualic acid CAS#:52809-07-1 |
Literature: Murakoshi, Isamu; Ikegami, Fumio; Koide, Chiharu Heterocycles, 1984 , vol. 21, # 2 p. 705 |
HS Code | 2934999090 |
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Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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L-Alanine, 3-(3-hydroxy-5-oxo-1,2,4-oxadiazol-2(5H)-yl)- |
L-Quisqualic acid |
L-Alanine, 3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)- |
1,2,4-Oxadiazolidine-2-propanoic acid, α-amino-3,5-dioxo-, (S)- |
MFCD00069337 |
3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine |
b-(3,5-Dioxo-1,2,4-oxodiazolidin-2-yl)-L-alanine |
L-(+)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic Acid |
(L)-(+)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid |
Quisqualic acid |
3-(3-Hydroxy-5-oxo-1,2,4-oxadiazol-2(5H)-yl)-L-alanine |
β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine |
L-Quisqualic acid,(L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoicacid |
(S)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic Acid |