2-Phenyl-isoindole-1,3-dione

Modify Date: 2024-01-03 19:19:26

2-Phenyl-isoindole-1,3-dione Structure
2-Phenyl-isoindole-1,3-dione structure
Common Name 2-Phenyl-isoindole-1,3-dione
CAS Number 520-03-6 Molecular Weight 223.227
Density 1.3±0.1 g/cm3 Boiling Point 388.8±25.0 °C at 760 mmHg
Molecular Formula C14H9NO2 Melting Point 204-207 °C(lit.)
MSDS Chinese USA Flash Point 182.6±15.5 °C

 Names

Name N-Phenylphthalimide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 388.8±25.0 °C at 760 mmHg
Melting Point 204-207 °C(lit.)
Molecular Formula C14H9NO2
Molecular Weight 223.227
Flash Point 182.6±15.5 °C
Exact Mass 223.063324
PSA 37.38000
LogP 2.40
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.667

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI5635800
CHEMICAL NAME :
Phthalimide, N-phenyl-
CAS REGISTRY NUMBER :
520-03-6
BEILSTEIN REFERENCE NO. :
0010683
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H9-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,23,1953

 Safety Information

Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TI5635800
HS Code 2925190090

 Synthetic Route

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles8

More Articles
Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening.

J. Med. Chem. 54 , 5454, (2011)

To identify specific bacterial thymidylate synthase (TS) inhibitors, we exploited phenolphthalein (PTH), which inhibits both bacterial and human enzymes. The X-ray crystal structure of Lactobacillus c...

Phenylphthalimides with tumor necrosis factor alpha production-enhancing activity.

Chem. Pharm. Bull. 44(1) , 156-62, (1996)

Phenylphthalimides (2-phenyl-1H-isoindole-1,3-diones) were prepared and their effects on tumor necrosis factor alpha (TNF-alpha) production by human leukemia cell line HL-60 stimulated with 12-O-tetra...

Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs.

Bioorg. Med. Chem. Lett. 9(4) , 559-62, (1999)

A novel series of nonpeptide small-molecular dipeptidyl peptidase IV (DPP-IV) inhibitors with an N-phenylphthalimide skeleton has been developed. Some of the compounds, including 4-amino-(2,6-dimethyl...

 Synonyms

EINECS 208-282-9
2-Phenyl-1H-isoindole-1,3(2H)-dione
1H-Isoindole-1,3(2H)-dione, 2-phenyl-
2-Phenylisoindole-1,3-dione
2-Phenyl-isoindole-1,3-dione
MFCD00023044
N-PHENYLPHTHALIMIDE