LHRH (4-10) acetate salt

Modify Date: 2025-08-25 15:50:22

LHRH (4-10) acetate salt Structure
LHRH (4-10) acetate salt structure
 Common Name LHRH (4-10) acetate salt
CAS Number 51776-33-1 Molecular Weight 747.84200
Density N/A Boiling Point N/A
Molecular Formula C33H53N11O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LHRH (4-10) acetate salt


LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes[1].

 Names

Name 1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide$GLP-HIS-TYR-SER-LEU-GLU-TRP-LYS-PRO-GLY-NH2
Synonym More Synonyms

 LHRH (4-10) acetate salt Biological Activity

Description LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes[1].
Related Catalog
In Vitro The formation of LHRH 4-10, LHRH 7-10, and LHRH 6-10Co-incubation are inhibited by known enzyme inhibitors including Captopril (HY-B0368) (an ACE inhibitor), Thiorphan (HY-W013375) (an EP24.11 inhibitor), and Ethylenediaminetetraacetic acid (HY-Y0682) (an EP24.15 inhibitor)[1]. LH-RH (4-10) inhibits the binding of 125I-labeled GnRH to monoclonal antibody P81662 with an IC50 value of 23 pM[2].

 Chemical & Physical Properties

Molecular Formula C33H53N11O9
Molecular Weight 747.84200
Exact Mass 747.40300
PSA 337.28000
LogP 0.21070

 Safety Information

Hazard Codes T
Risk Phrases 60
Safety Phrases 53-22-36/37/39-45
WGK Germany 3

 Synthetic Route

 Synonyms

Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Luteinizing hormone releasing hormone Fragment 4-10
LH-RH Fragment 4-10
LHRH (4-10)
H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
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