Metoprolol

Modify Date: 2024-01-09 17:28:32

Metoprolol Structure
Metoprolol structure
Common Name Metoprolol
CAS Number 51384-51-1 Molecular Weight 267.364
Density 1.0±0.1 g/cm3 Boiling Point 398.6±37.0 °C at 760 mmHg
Molecular Formula C15H25NO3 Melting Point N/A
MSDS N/A Flash Point 194.9±26.5 °C

 Use of Metoprolol


Metoprolol (Toprol) is a selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension.IC50 value:Target: β1 receptor

 Names

Name Metoprolol
Synonym More Synonyms

 Metoprolol Biological Activity

Description Metoprolol (Toprol) is a selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension.IC50 value:Target: β1 receptor
Related Catalog
References

[1]. Benfield P, et al. Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. Drugs. 1986 May;31(5):376-429.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 398.6±37.0 °C at 760 mmHg
Molecular Formula C15H25NO3
Molecular Weight 267.364
Flash Point 194.9±26.5 °C
Exact Mass 267.183441
PSA 50.72000
LogP 1.79
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.508

 Safety Information

HS Code 2922509090

 Synthetic Route

~90%

Metoprolol Structure

Metoprolol

CAS#:51384-51-1

Literature: IPCA LABORATORIES LIMITED Patent: WO2005/46568 A2, 2005 ; Location in patent: Page/Page column 6-8 ;

~93%

Metoprolol Structure

Metoprolol

CAS#:51384-51-1

Literature: Massachusetts Institute of Technology Patent: US2011/118469 A1, 2011 ; Location in patent: Page/Page column 10-11 ;

~%

Metoprolol Structure

Metoprolol

CAS#:51384-51-1

Literature: Sukuraba; Takahashi; Takeda; Achiwa Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 5 p. 738 - 747

~%

Metoprolol Structure

Metoprolol

CAS#:51384-51-1

Literature: Baeckvall, Jan-E.; Bystroem, Styrbjoern E. Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 1126 - 1128

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Medrol
Medrate
Metilbetasone
(2S)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
methylprednisolone
Solomet
2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-, (2S)-
Dopomedrol
Promacortine
Medrone
2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2S)-
(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
Urbason
Besonia
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