Metoprolol

Names

[ Name ]:
Metoprolol

[Synonym ]:
Medrol
Medrate
Metilbetasone
(2S)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
methylprednisolone
Solomet
2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-, (2S)-
Dopomedrol
Promacortine
Medrone
2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2S)-
(2S)-1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
Urbason
Besonia

Biological Activity

[Description]:

Metoprolol (Toprol) is a selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension.IC50 value:Target: β1 receptor

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Cardiovascular Disease

Natural Products >> Others

[References]

[1]. Benfield P, et al. Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. Drugs. 1986 May;31(5):376-429.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
398.6±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₅NO₃

[ Molecular Weight ]:
267.364

[ Flash Point ]:
194.9±26.5 °C

[ Exact Mass ]:
267.183441

[ PSA ]:
50.72000

[ LogP ]:
1.79

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.508

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%