2-Hydroxy Ibuprofen

Modify Date: 2025-08-21 09:48:22

2-Hydroxy Ibuprofen Structure
2-Hydroxy Ibuprofen structure
Common Name 2-Hydroxy Ibuprofen
CAS Number 51146-55-5 Molecular Weight 222.28000
Density 1.125 g/cm3 Boiling Point 369.4ºC at 760 mmHg
Molecular Formula C13H18O3 Melting Point 120-122ºC
MSDS Chinese USA Flash Point N/A

 Use of 2-Hydroxy Ibuprofen


2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

 Names

Name rac 2-Hydroxy Ibuprofen
Synonym More Synonyms

 2-Hydroxy Ibuprofen Biological Activity

Description 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
Related Catalog
References

[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

 Chemical & Physical Properties

Density 1.125 g/cm3
Boiling Point 369.4ºC at 760 mmHg
Melting Point 120-122ºC
Molecular Formula C13H18O3
Molecular Weight 222.28000
Exact Mass 222.12600
PSA 57.53000
LogP 2.18810
Index of Refraction 1.543
InChIKey UJHKVYPPCJBOSG-UHFFFAOYSA-N
SMILES CC(C(=O)O)c1ccc(CC(C)(C)O)cc1
Storage condition -20°C Freezer

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2918199090

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propionic acid
2-[4-(2-hydroxy-2-methylpropyl)phenyl]propanoic acid
2-Hydroxyibuprofen
Ibuprofen Impurity 19
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