DC Chemicals Limited
China
Product Name: 2-Hydroxy Ibuprofen
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: 2-Hydroxyibuprofen
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

51146-55-5

51146-55-5 structure

51146-55-5 structure

Name: 2-Hydroxy Ibuprofen
Chemical Name: rac 2-Hydroxy Ibuprofen
CAS Number: 51146-55-5
Molecular Formula: C₁₃H₁₈O₃
Molecular Weight: 222.28000
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2016-06-09 11:35:15
Modify Date: 2024-01-05 14:59:41
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

Name	rac 2-Hydroxy Ibuprofen
Synonyms	2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propionic acid 2-[4-(2-hydroxy-2-methylpropyl)phenyl]propanoic acid 2-Hydroxyibuprofen Ibuprofen Impurity 19

Description	2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
References	[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

Density	1.125 g/cm3
Boiling Point	369.4ºC at 760 mmHg
Melting Point	120-122ºC
Molecular Formula	C₁₃H₁₈O₃
Molecular Weight	222.28000
Exact Mass	222.12600
PSA	57.53000
LogP	2.18810
Index of Refraction	1.543
Storage condition	-20°C Freezer

RIDADR	NONH for all modes of transport
HS Code	2918199090

75626-01-6 structure

75626-01-6

~99%

51146-55-5 structure

51146-55-5

Literature: Kurtz, Richard R.; Houser, David J. Journal of Organic Chemistry, 1981 , vol. 46, # 1 p. 202 - 203

75625-98-8 structure

75625-98-8

~%

51146-55-5 structure

51146-55-5

Literature: Kurtz, Richard R.; Houser, David J. Journal of Organic Chemistry, 1981 , vol. 46, # 1 p. 202 - 203

75626-00-5 structure

75626-00-5

~%

51146-55-5 structure

51146-55-5

Literature: Kurtz, Richard R.; Houser, David J. Journal of Organic Chemistry, 1981 , vol. 46, # 1 p. 202 - 203

15687-27-1 structure

15687-27-1

~15%

51146-55-5 structure

51146-55-5

Literature: Segrestaa, Jerome; Verite, Philippe; Estour, Francois; Menager, Sabine; Lafont, Olivier Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 6 p. 744 - 748

15687-27-1 structure

15687-27-1

~%

53949-53-4 structure

53949-53-4

51146-55-5 structure

51146-55-5

Literature: Poraj-Kobielska, Marzena; Kinne, Matthias; Ullrich, Rene; Scheibner, Katrin; Kayser, Gernot; Hammel, Kenneth E.; Hofrichter, Martin Biochemical Pharmacology, 2011 , vol. 82, # 7 p. 789 - 796

75625-99-9 structure

75625-99-9

~%

51146-55-5 structure

51146-55-5

Literature: Kurtz, Richard R.; Houser, David J. Journal of Organic Chemistry, 1981 , vol. 46, # 1 p. 202 - 203

Precursor 5
75626-01-6 75625-99-9 75625-98-8 75626-00-5
15687-27-1
DownStream 0

HS Code	2918199090
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%