5-Bromouracil

Modify Date: 2024-01-02 13:43:28

5-Bromouracil Structure
5-Bromouracil structure
Common Name 5-Bromouracil
CAS Number 51-20-7 Molecular Weight 190.98
Density 2.0±0.1 g/cm3 Boiling Point 384ºC
Molecular Formula C4H3BrN2O2 Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of 5-Bromouracil


5-Bromouracil is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 5-bromouracil
Synonym More Synonyms

 5-Bromouracil Biological Activity

Description 5-Bromouracil is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 5-溴尿嘧啶通过诱导 A 型样 DNA 破坏核小体定位。

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 384ºC
Melting Point >300 °C(lit.)
Molecular Formula C4H3BrN2O2
Molecular Weight 190.98
Exact Mass 189.937775
PSA 65.72000
LogP -0.35
Index of Refraction 1.590
Water Solubility SOLUBLE IN COLD WATER

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ9060000
CHEMICAL NAME :
Uracil, 5-bromo-
CAS REGISTRY NUMBER :
51-20-7
LAST UPDATED :
199709
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C4-H3-Br-N2-O2
MOLECULAR WEIGHT :
191.00
WISWESSER LINE NOTATION :
T6MVMVJ EE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1700 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
5 gm/kg/2W-I
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
400 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TEST SYSTEM :
Insect - grasshopper
DOSE/DURATION :
10 mg
REFERENCE :
IDZAAW Japanese Journal of Genetics. Idengaku Zasshi. (Genetics Soc. of Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan) V.1- 1921- Volume(issue)/page/year: 38,305,1963

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R46
Safety Phrases S36/37-S53-S45
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YQ9060000
HS Code 29335995

 Synthetic Route

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

Uracil,5-bromo
2,4(1H,3H)-Pyrimidinedione, 5-bromo-
Bromouracil
5-Bromo-2,4(1H,3H)-pyrimidinedione
5-bromo-uraci
5-bromopyrimidine-2,4-diol
5-bromo-2,4-dioxopyrimidine
5-Bromouracil
5-BrUra
5-Br-uracil
BROMOURACIL,5
5-bromo-uracil
EINECS 200-084-0
MFCD00006017
5-bromopyrimidine-2,4(1H,3H)-dione
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