2-Methoxy-2,4-diphenyl-3(2H)-furanone

Modify Date: 2024-01-30 23:53:32

2-Methoxy-2,4-diphenyl-3(2H)-furanone Structure
2-Methoxy-2,4-diphenyl-3(2H)-furanone structure
Common Name 2-Methoxy-2,4-diphenyl-3(2H)-furanone
CAS Number 50632-57-0 Molecular Weight 266.291
Density 1.2±0.1 g/cm3 Boiling Point 426.6±45.0 °C at 760 mmHg
Molecular Formula C17H14O3 Melting Point 96ºC
MSDS Chinese USA Flash Point 203.6±15.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 2-Methoxy-2,4-diphenyl-3(2H)-furanone


2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography[1].

 Names

Name 2-methoxy-2,4-diphenylfuran-3-one
Synonym More Synonyms

 2-Methoxy-2,4-diphenyl-3(2H)-furanone Biological Activity

Description 2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography[1].
Related Catalog
References

[1]. Peter Jackson. Detection of phosphoproteins. WO2006070180.

[2]. Danqing Min, et al. 2-Methoxy-2,4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: a rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases. Electrophoresis. 20

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 426.6±45.0 °C at 760 mmHg
Melting Point 96ºC
Molecular Formula C17H14O3
Molecular Weight 266.291
Flash Point 203.6±15.1 °C
Exact Mass 266.094299
PSA 35.53000
LogP 3.48
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.618
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2932190090

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles22

More Articles
Proteolytic activity and cytokine up-regulation by non-albicans Candida albicans.

Arch. Microbiol. 197(4) , 533-7, (2015)

Mouth is an important source of infections and oral infections such as Candida infections increase the risk of mortality. Our purpose was to investigate differences in proteolytic activity of non-albi...

Fluorescent labeling of proteins with nile red and 2-methoxy-2,4-diphenyl-3(2H)-furanone: physicochemical basis and application to the rapid staining of sodium dodecyl sulfate polyacrylamide gels and Western blots.

Electrophoresis 22(5) , 874-80, (2001)

The fluorescent hydrophobic dye Nile red allows the rapid, sensitive, and general staining of proteins in sodium dodecyl sulfate (SDS)-polyacrylamide gels. Nile red staining does not preclude further ...

Rapid imaging, using a cooled charge-coupled-device, of fluorescent two-dimensional polyacrylamide gels produced by labelling proteins in the first-dimensional isoelectric focusing gel with the fluorophore 2-methoxy-2,4-diphenyl-3(2H)furanone.

Electrophoresis 9(7) , 330-9, (1988)

A new method for visualising proteins in two-dimensional polyacrylamide gels was developed. Proteins were labelled with the fluorophore 2-methoxy-2,4-diphenyl-3(2H)furanone (MDPF) while present in the...

 Synonyms

2-Methoxy-2,4-diphenylfuran-3(2H)-one
MFCD00036834
3(2H)-Furanone, 2-methoxy-2,4-diphenyl-
2-Mdpf
2-Methoxy-2,4-diphenyl-3(2H)-furanone
MDPF
2,4-Diphenyl-2-methoxy-3(2H)-furanone,MDPF
2-methoxy-2,4-diphenyl-furan-3-one