Sorbitol

Sorbitol Structure
Sorbitol
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Common Name Sorbitol
CAS Number 50-70-4 Molecular Weight 182.172
Density 1.6±0.1 g/cm3 Boiling Point 494.9±0.0 °C at 760 mmHg
Molecular Formula C6H14O6 Melting Point 95-99ºC
MSDSSorbitol MSDS|SDS|pdf download USA Flash Point 292.5±23.3 °C

 Names

[ Name ]: D-glucitol
[ Synonym ]: More Synonyms

 Chemical & Physical Properties

[ Density ]: 1.6±0.1 g/cm3
[ Boiling Point ]: 494.9±0.0 °C at 760 mmHg
[ Melting Point ]: 95-99ºC
[ Molecular Formula ]: C6H14O6
[ Molecular Weight ]: 182.172
[ Flash Point ]: 292.5±23.3 °C
[ Exact Mass ]: 182.079041
[ PSA ]: 121.38000
[ LogP ]: -4.67
[ Vapour Pressure ]: 0.0±2.8 mmHg at 25°C
[ Index of Refraction ]: 1.597

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ4290000
CHEMICAL NAME :
Glucitol
CAS REGISTRY NUMBER :
50-70-4
LAST UPDATED :
199701
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C6-H14-O6
MOLECULAR WEIGHT :
182.20
WISWESSER LINE NOTATION :
Q1YQYQYQYQ1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
1700 mg/kg/D
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
29600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
17800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
24 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9480 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
300 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 189,15,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80530 No. of Facilities: 16621 (estimated) No. of Industries: 86 No. of Occupations: 80 No. of Employees: 144563 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80530 No. of Facilities: 18220 (estimated) No. of Industries: 126 No. of Occupations: 121 No. of Employees: 669284 (estimated) No. of Female Employees: 461984 (estimated)

 Safety Information

[ Personal Protective Equipment ]: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]: Xi
[ Risk Phrases ]: 36/37/38
[ Safety Phrases ]: S8
[ RIDADR ]: NONH for all modes of transport
[ RTECS ]: LZ4290000
[ HS Code ]: 2905440000

 Synthetic Route

 Customs

[ HS Code ]: 2905440000

 Articles322

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