(S)-Salsolidine

Modify Date: 2024-01-08 16:07:52

(S)-Salsolidine structure	Common Name	(S)-Salsolidine
	CAS Number	493-48-1	Molecular Weight	207.27
	Density	1.034g/cm3	Boiling Point	313.4ºC at 760mmHg
	Molecular Formula	C₁₂H₁₇NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	127.1ºC

Use of (S)-Salsolidine

(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (Ki=63 μM). The R enantiomer of Salsolidine is more potent than the S form (Ki=26 μM)[1].

Name	salsolidine
Synonym	More Synonyms

Description	(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (Ki=63 μM). The R enantiomer of Salsolidine is more potent than the S form (Ki=26 μM)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	Human Endogenous Metabolite
In Vitro	Salsolidine is a dopamine-derived tetrahydroisoquinoline-alkaloid which possesses an asymmetric center at C-1 and exists as R and S enantiomers[1].
References	[1]. Dostert P, et al. Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases. J Neural Transm. 1988;74(2):61-74.

Density	1.034g/cm3
Boiling Point	313.4ºC at 760mmHg
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27
Flash Point	127.1ºC
Exact Mass	207.12600
PSA	30.49000
LogP	2.23930
Vapour Pressure	0.000496mmHg at 25°C
Index of Refraction	1.509

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX5018500

CHEMICAL NAME :: Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-

CAS REGISTRY NUMBER :: 493-48-1

LAST UPDATED :: 199312

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H17-N-O2

MOLECULAR WEIGHT :: 207.30

WISWESSER LINE NOTATION :: T66 CMT&J B1 HO1 IO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 41,249,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 15(2),54,1981

Precursor 0
DownStream 4
CAS#:4721-98-6 6,7-Dimethoxy-1... CAS#:493-48-1 (S)-Salsolidine CAS#:38221-21-5 6,7-DIHYDROXY-1... CAS#:525-72-4 (R)-1-METHYL-1,...

rac-salsolidine

6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE

1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylisoquinoline

1-methyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline

DC Chemicals Limited
China
Product Name: (S)-Salsolidine
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: SALSOLIDINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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