SNAP-94847 hydrochloride

Modify Date: 2024-01-06 23:24:55

SNAP-94847 hydrochloride structure	Common Name	SNAP-94847 hydrochloride
	CAS Number	487051-12-7	Molecular Weight	515.03400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₃ClF₂N₂O₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS09	Signal Word	Warning

Use of SNAP-94847 hydrochloride

SNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCH1) antagonist with antidepressant-like activity, it differentiates from classic anxiolytic and antidepressant drugs.SNAP 94847 binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.SNAP 94847 is a high affinity antagonist (pA2 = 7.81) of MCH-evoked inositol phosphate formation[1].

Name	N-(3-{1-[4-(3,4-Difluorophenoxy)benzyl]-4-piperidinyl}-4-methylph enyl)-2-methylpropanamide hydrochloride (1:1)
Synonym	More Synonyms

Description	SNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCH1) antagonist with antidepressant-like activity, it differentiates from classic anxiolytic and antidepressant drugs.SNAP 94847 binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.SNAP 94847 is a high affinity antagonist (pA2 = 7.81) of MCH-evoked inositol phosphate formation[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> MCHR1 (GPR24) Research Areas >> Neurological Disease
References	[1]. David DJ, et al. Efficacy of the MCHR1 antagonist N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in mouse models of anxiety and depression following acute and chronic administration is independent of hippocampal neurogenesis. J Pharmacol Exp Ther. 2007 Apr;321(1):237-48. Epub 2007 Jan 19.

Molecular Formula	C₂₉H₃₃ClF₂N₂O₂
Molecular Weight	515.03400
Exact Mass	514.22000
PSA	45.06000
LogP	8.42900

SNAP-94847 hydrochloride MSDS(Chinese)

Symbol	GHS09
Signal Word	Warning
Hazard Statements	H410
Precautionary Statements	P273-P501
RIDADR	UN 3077 9 / PGIII

BW 723C86 hydrochloride

DC Chemicals Limited
China
Product Name: SNAP-94847 hydrochloride
Price: $650.0/100mg $1200.0/250mg $2300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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