Amde-1

Modify Date: 2025-09-24 11:38:52

Amde-1 Structure
Amde-1 structure
Common Name Amde-1
CAS Number 478043-30-0 Molecular Weight 415.72
Density N/A Boiling Point N/A
Molecular Formula C18H8ClF6N3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amde-1


AMDE-1 is a potent autophagy inducer. AMDE-1 induces autophagy by the AMPK-mTORC1-ULK1 pathway and at the same time inhibited autophagy-mediated degradation by causing lysosome dysfunction. AMDE-1 can be used in research of cancer[1].

 Names

Name AMDE-1

 Amde-1 Biological Activity

Description AMDE-1 is a potent autophagy inducer. AMDE-1 induces autophagy by the AMPK-mTORC1-ULK1 pathway and at the same time inhibited autophagy-mediated degradation by causing lysosome dysfunction. AMDE-1 can be used in research of cancer[1].
Related Catalog
References

[1]. Li M, et, al. AMDE-1 is a dual function chemical for autophagy activation and inhibition. PLoS One. 2015 Apr 20;10(3):e0122083.  

 Chemical & Physical Properties

Molecular Formula C18H8ClF6N3
Molecular Weight 415.72
InChIKey QPWWAOMXYPIDOY-UHFFFAOYSA-N
SMILES N#CC(c1cccc(Cl)c1)c1ccc2c(C(F)(F)F)cc(C(F)(F)F)nc2n1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.