478043-30-0

478043-30-0 structure

Name: Amde-1
Chemical Name: AMDE-1
CAS Number: 478043-30-0
Molecular Formula: C₁₈H₈ClF₆N₃
Molecular Weight: 415.72
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2023-11-11 23:21:55
Modify Date: 2025-09-24 11:38:52
AMDE-1 is a potent autophagy inducer. AMDE-1 induces autophagy by the AMPK-mTORC1-ULK1 pathway and at the same time inhibited autophagy-mediated degradation by causing lysosome dysfunction. AMDE-1 can be used in research of cancer[1].

Name	AMDE-1

Description	AMDE-1 is a potent autophagy inducer. AMDE-1 induces autophagy by the AMPK-mTORC1-ULK1 pathway and at the same time inhibited autophagy-mediated degradation by causing lysosome dysfunction. AMDE-1 can be used in research of cancer[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> PI3K/Akt/mTOR >> AMPK
References	[1]. Li M, et, al. AMDE-1 is a dual function chemical for autophagy activation and inhibition. PLoS One. 2015 Apr 20;10(3):e0122083.

Molecular Formula	C₁₈H₈ClF₆N₃
Molecular Weight	415.72