Amde-1

Names

[ Name ]:
Amde-1

Biological Activity

[Description]:

AMDE-1 is a potent autophagy inducer. AMDE-1 induces autophagy by the AMPK-mTORC1-ULK1 pathway and at the same time inhibited autophagy-mediated degradation by causing lysosome dysfunction. AMDE-1 can be used in research of cancer[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> AMPK

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

[References]

[1]. Li M, et, al. AMDE-1 is a dual function chemical for autophagy activation and inhibition. PLoS One. 2015 Apr 20;10(3):e0122083.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₈ClF₆N₃

[ Molecular Weight ]:
415.72

Related Compounds

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