Ruscogenin

Modify Date: 2025-08-21 08:15:17

Ruscogenin Structure
Ruscogenin structure
 Common Name Ruscogenin
CAS Number 472-11-7 Molecular Weight 430.62
Density 1.2±0.1 g/cm3 Boiling Point 563.1±50.0 °C at 760 mmHg
Molecular Formula C27H42O4 Melting Point 198-202ºC
MSDS Chinese USA Flash Point 294.4±30.1 °C

 Use of Ruscogenin


Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities[1][2].

 Names

Name Ruscogenin
Synonym More Synonyms

 Ruscogenin Biological Activity

Description Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities[1][2].
Related Catalog
References

[1]. Cao G, et al. Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway. Int J Mol Sci. 2016 Aug 29;17(9). pii: E1418.

[2]. Huang YL, et al. Possible mechanism of the anti-inflammatory activity of ruscogenin: role of intercellular adhesion molecule-1 and nuclear factor-kappaB. J Pharmacol Sci. 2008 Oct;108(2):198-205.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 563.1±50.0 °C at 760 mmHg
Melting Point 198-202ºC
Molecular Formula C27H42O4
Molecular Weight 430.62
Flash Point 294.4±30.1 °C
Exact Mass 430.308319
PSA 58.92000
LogP 4.29
Vapour Pressure 0.0±3.5 mmHg at 25°C
Index of Refraction 1.577
Storage condition 2~8℃

 Safety Information

Hazard Codes Xi
Safety Phrases 24/25
RIDADR NONH for all modes of transport
HS Code 29389090

 Synthetic Route

 Synonyms

(1β,3β,25R)-Spirost-5-ene-1,3-diol
25D-Spirost-5-ene-1|A,3|A-diol
(25R)-Spirost-5-ene-1b,3b-diol
(25R)-Spirost-5-ene-1β,3β-diol
(1β,3β,25R)-Spirost-5-en-1,3-diol
Spirost-5-en-1,3-diol, (1β,3β,25R)-
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Ruscogenin suppliers

Ruscogenin price

Related Compounds: More...
NEORUSCOGENIN
35882-30-5
(25RS)-Ruscogenin
874485-32-2
1-O-sulpho-ruscogenin
149439-66-7
3β-O-tert-butyldimethylsilyl-(25R)-ruscogenin
201858-23-3
25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside
125225-63-0
ruscogenin 1-O-[O-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside]
39491-38-8
ruscogenin 1-O-(β-D-glucopyranosyl(1->2))(β-D-xylopyranosyl(1->3))-β-D-fucopyranoside
128397-47-7
ruscogenin 1-O-(β-D-glucopyranosyl(1->2))(β-D-xylopyranosyl(1->3))-β-D-fucopyranoside
130551-41-6
25(S)-ruscogenin 1-O-β-D-xylopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-fucopyranoside
1486510-48-8
4-(4-Aminophenyl)hexahydro-1H-1,4-diazepine-1-ethanol
497249-53-3
(6S,8AS)-octahydroindolizin-6-ol
219667-09-1
Isoquinolinium, 2-[3-[(2-ethylhexyl)oxy]-2-(sulfooxy)propyl]-3,4-dihydro-, inner salt
634606-22-7
5-Hydroxy-2-methoxybenzonitrile
180526-90-3
2-Bromo-2-nitrobicyclo[2.2.1]heptane
183548-26-7
3,4,4-Trifluoro-3-butenoyl chloride
145342-83-2
N-[benzylimino-bis(dimethylamino)-lambda5-phosphanyl]-N-methylmethanamine
126307-69-5
Cycloheptyl-(5-phenyl-1H-pyrazol-3-ylmethyl)-amine
2737205-40-0
Prallethrin, (1R,4S)-cis-
114028-47-6
(4R,7aS,12bS)-6-chloro-9-methoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline
106556-37-0
Chemsrc provides Ruscogenin(CAS#:472-11-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Ruscogenin are included as well.>> amp version: Ruscogenin

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved