25(R,S)-Ruscogenin

Modify Date: 2024-01-11 02:18:01

25(R,S)-Ruscogenin Structure
25(R,S)-Ruscogenin structure
Common Name 25(R,S)-Ruscogenin
CAS Number 874485-32-2 Molecular Weight 430.62
Density N/A Boiling Point 563.1±50.0 °C(Predicted)
Molecular Formula C27H42O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 25(R,S)-Ruscogenin


Ruscogenin suppresses HCC metastasis by reducing the expression of MMP-2, MMP-9, uPA, VEGF and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway[1]. And Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by su

 Names

Name (25RS)-Ruscogenin
Synonym More Synonyms

 25(R,S)-Ruscogenin Biological Activity

Description Ruscogenin suppresses HCC metastasis by reducing the expression of MMP-2, MMP-9, uPA, VEGF and HIF-1α via regulating the PI3K/Akt/mTOR signaling pathway[1]. And Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by su
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References

[1]. Hua H, Zhu Y, Song YH. Ruscogenin suppressed the hepatocellular carcinoma metastasis via PI3K/Akt/mTOR signaling pathway. Biomed Pharmacother. 2018;101:115-122.

[2]. Wu Y, Wang Y, Gong S, et al. Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling. Biomed Pharmacother. 2020;125:109868.

 Chemical & Physical Properties

Boiling Point 563.1±50.0 °C(Predicted)
Molecular Formula C27H42O4
Molecular Weight 430.62

 Safety Information

Hazard Codes Xi

 Synonyms

Spirost-5-ene-1,3-diol,(1β,3β)- (9CI)