NH2-O-C5-COOH hydrobromide

Modify Date: 2025-08-25 20:28:04

NH2-O-C5-COOH hydrobromide Structure
NH2-O-C5-COOH hydrobromide structure
Common Name NH2-O-C5-COOH hydrobromide
CAS Number 448954-98-1 Molecular Weight 228.08400
Density N/A Boiling Point 349.5ºC at 760 mmHg
Molecular Formula C6H14BrNO3 Melting Point N/A
MSDS N/A Flash Point 165.2ºC

 Use of NH2-O-C5-COOH hydrobromide


NH2-O-C5-COOH (hydrobromide) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 6-aminooxyhexanoic acid,hydrobromide
Synonym More Synonyms

 NH2-O-C5-COOH hydrobromide Biological Activity

Description NH2-O-C5-COOH (hydrobromide) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Boiling Point 349.5ºC at 760 mmHg
Molecular Formula C6H14BrNO3
Molecular Weight 228.08400
Flash Point 165.2ºC
Exact Mass 227.01600
PSA 72.55000
LogP 2.18010

 Synonyms

6-Aminooxy-hexanoic acid hydrobromide
6-Aminooxy-hexanoic acid
Hexanoicacid,6-(aminooxy)-,hydrobromide (1:1)
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