Modified MMAF-C5-COOH

Modify Date: 2025-09-10 11:57:44

Modified MMAF-C5-COOH structure	Common Name	Modified MMAF-C5-COOH
	CAS Number	1404071-65-3	Molecular Weight	954.25
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₁H₈₃N₇O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Modified MMAF-C5-COOH

Modified MMAF-C5-COOH is a drug-linker conjugate for ADC[1].

Name	Modified MMAF-C5-COOH

Description	Modified MMAF-C5-COOH is a drug-linker conjugate for ADC[1].
Related Catalog	Research Areas >> Cancer
In Vitro	MMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC50s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay[2].
References	[1]. Polson AG, et al. Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection [published correction appears in Cancer Res. 2010 Feb 1;70(3):1275. Slaga, Dion S [added]]. Cancer Res. 2009;69(6):2358-2364. [2]. Doronina SO, et al. Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity. Bioconjug Chem. 2006;17(1):114-124.

Molecular Formula	C₅₁H₈₃N₇O₁₀
Molecular Weight	954.25
InChIKey	NQGJJAVKWZWPGE-DVHZIZCVSA-N
SMILES	CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCCCO1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)CCCCCC(=O)O)C(C)C

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Modified MMAF-C5-COOH
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Modified MMAF-C5-COOH
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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