2229976-21-8

2229976-21-8 structure

Name: (S,R,S)-AHPC-Me-C5-COOH
Chemical Name: (S,R,S)-AHPC-Me-C5-COOH
CAS Number: 2229976-21-8
Molecular Formula: C₃₀H₄₂N₄O₆S
Molecular Weight: 586.74
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-04-11 21:24:35
Modify Date: 2025-08-23 20:51:30
(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].

Name	(S,R,S)-AHPC-Me-C5-COOH

Description	(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	DT2216 is a selective B-cell lymphoma extra large (BCL-XL) PROTAC degrader[1].
References	[1]. Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.

Molecular Formula	C₃₀H₄₂N₄O₆S
Molecular Weight	586.74

Hazard Codes	Xi