COUMERMYCIN AL
COUMERMYCIN AL structure
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Common Name | COUMERMYCIN AL | ||
|---|---|---|---|---|
| CAS Number | 4434-05-3 | Molecular Weight | 1110.08000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C55H59N5O20 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of COUMERMYCIN ALCoumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. |
| Name | coumermycin A1 |
|---|---|
| Synonym | More Synonyms |
| Description | Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. |
|---|---|
| Related Catalog | |
| In Vitro | Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea leptin receptor mRNA level[1]. |
| References |
| Molecular Formula | C55H59N5O20 |
|---|---|
| Molecular Weight | 1110.08000 |
| Exact Mass | 1109.38000 |
| PSA | 354.89000 |
| LogP | 5.71790 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Precursor 9 | |
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| DownStream 0 | |
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CAS#:374749-49-2|
Multiplexing interactions to control antibiotic release from cyclodextrin hydrogels.
Macromol. Biosci. 11(11) , 1544-52, (2011) A new strategy for affinity-based drug delivery by modification of the drug rather than modification of the device is presented. Rifampin is modified to contain either one or two PEG-adamantane arms, ... |
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Aminocoumarins inhibit osteoclast differentiation and bone resorption via downregulation of nuclear factor of activated T cells c1.
Biochem. Pharmacol. 85(3) , 417-25, (2013) Aminocoumarins, such as coumermycin A1 and novobiocin, are natural products of streptomycetes. They are potent inhibitors of bacterial DNA gyrase and are used to suppress the growth of bacteria in inf... |
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Modulation of chaperone function and cochaperone interaction by novobiocin in the C-terminal domain of Hsp90: evidence that coumarin antibiotics disrupt Hsp90 dimerization.
J. Biol. Chem. 281 , 7161-7171, (2006) The C-terminal domain of Hsp90 displays independent chaperone activity, mediates dimerization, and contains the MEEVD motif essential for interaction with tetratricopeptide repeat-containing immunophi... |
| coumamycin |
| l)oxy)-4-hydroxy-8-methylcoumarin) |
| Sugordomycin D-la |
| Coumermycin |
| Cumamycin |
| coumermycins |
| notomycina1 |
| COUMERMYCIN A1 |
| Notomycin |