Besifovir Dipivoxil maleate

Modify Date: 2024-01-11 12:11:07

Besifovir Dipivoxil maleate Structure
Besifovir Dipivoxil maleate structure
Common Name Besifovir Dipivoxil maleate
CAS Number 441785-26-8 Molecular Weight 527.50800
Density N/A Boiling Point N/A
Molecular Formula C26H38N5O12P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Besifovir Dipivoxil maleate


Besifovir Dipivoxil maleate (LB80380 maleate) is an oral prodrug of LB80317. Besifovir Dipivoxil maleate (LB80380 maleate) is effective in hepatitis B virus (HBV) DNA suppression for both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients in preliminary studies[1][2]

 Names

Name lb-80380
Synonym More Synonyms

 Besifovir Dipivoxil maleate Biological Activity

Description Besifovir Dipivoxil maleate (LB80380 maleate) is an oral prodrug of LB80317. Besifovir Dipivoxil maleate (LB80380 maleate) is effective in hepatitis B virus (HBV) DNA suppression for both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients in preliminary studies[1][2]
Related Catalog
References

[1]. Yuen MF, et al. A randomized placebo-controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B. Antivir Ther. 2006;11(8):977-83.

[2]. Lai CL, et al. Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B. Gut. 2014 Jun;63(6):996-1004.

 Chemical & Physical Properties

Molecular Formula C26H38N5O12P
Molecular Weight 527.50800
Exact Mass 527.21400
PSA 176.79000
LogP 3.81630

 Synonyms

({1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl}oxy)methylphosphonic acid dipivoxyl
2,2-Dimethyl-propionic acid [1-(2-amino-purin-9-ylmethyl)-cyclopropoxymethyl]-(2,2-dimethyl-propionyloxymethoxy)-phosphinoyloxymethyl ester
3-[({1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl}oxy)methyl]-8,8-dimethyl-3,7-dioxo-2,4,6-trioxa-3λ5-phosphanon-1-yl-pivalate
9-[1-(phosphonomethoxycyclopropyl)methyl]-6-deoxyguanine
3-[({1-[(2-amino-9H-purin-9-yl)methyl]cyclopropyl}oxy)methyl]-8,8-dimethyl-3,7-dioxo-2,4,6-trioxa-3λ5-phosphanon-1-yl pivalate
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Besifovir
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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