N6-(2-Hydroxyethyl)adenosine

Modify Date: 2024-01-09 10:14:23

N6-(2-Hydroxyethyl)adenosine structure	Common Name	N6-(2-Hydroxyethyl)adenosine
	CAS Number	4338-48-1	Molecular Weight	311.29
	Density	1.88g/cm3	Boiling Point	725.8ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₇N₅O₅	Melting Point	194-195ºC
	MSDS	N/A	Flash Point	392.7ºC

Use of N6-(2-Hydroxyethyl)adenosine

N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Synonym	More Synonyms

Description	N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.88g/cm3
Boiling Point	725.8ºC at 760 mmHg
Melting Point	194-195ºC
Molecular Formula	C₁₂H₁₇N₅O₅
Molecular Weight	311.29
Flash Point	392.7ºC
Exact Mass	311.12300
PSA	145.78000
Index of Refraction	1.806