5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine

Modify Date: 2023-09-08 11:02:04

5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine structure	Common Name	5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine
	CAS Number	42867-74-3	Molecular Weight	252.22
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₂N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine

5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	[(2S,5R)-5-(2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl acetate
Synonym	More Synonyms

Description	5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₁H₁₂N₂O₅
Molecular Weight	252.22
Exact Mass	252.07500
PSA	90.65000

Precursor 0
DownStream 5
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