Uridine, 2',3'-didehydro-2',3'-dideoxy-5-fluoro- (9CI) structure
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Common Name | Uridine, 2',3'-didehydro-2',3'-dideoxy-5-fluoro- (9CI) | ||
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| CAS Number | 15379-29-0 | Molecular Weight | 228.18 | |
| Density | 1.57g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H9FN2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Uridine, 2',3'-didehydro-2',3'-dideoxy-5-fluoro- (9CI)2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
| Description | 2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 1.57g/cm3 |
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| Molecular Formula | C9H9FN2O4 |
| Molecular Weight | 228.18 |
| Exact Mass | 228.05500 |
| PSA | 84.32000 |
| Index of Refraction | 1.609 |
| InChIKey | SHVSSJHFEDAZCZ-UHFFFAOYSA-N |
| SMILES | O=c1[nH]c(=O)n(C2C=CC(CO)O2)cc1F |
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~75%
Uridine, 2',3'-... CAS#:15379-29-0 |
| Literature: Joshi, Bhalchandra V.; Rao, T. Sudhakar; Reese, Colin B. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 19 p. 2537 - 2544 |
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~%
Uridine, 2',3'-... CAS#:15379-29-0 |
| Literature: Coe, Paul L.; Talekar, Ratnakar R.; Walker, Richard T. Journal of Fluorine Chemistry, 1994 , vol. 69, # 1 p. 19 - 24 |
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~%
Uridine, 2',3'-... CAS#:15379-29-0 |
| Literature: Joshi, Bhalchandra V.; Rao, T. Sudhakar; Reese, Colin B. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 19 p. 2537 - 2544 |
| Precursor 3 | |
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| DownStream 0 | |
| 2',3'-Didehydro-2',3'-dideoxy-hexopyranosyl cytidine |