(E)-Guggulsterone
(E)-Guggulsterone structure
|
Common Name | (E)-Guggulsterone | ||
|---|---|---|---|---|
| CAS Number | 39025-24-6 | Molecular Weight | 312.446 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 463.3±45.0 °C at 760 mmHg | |
| Molecular Formula | C21H28O2 | Melting Point | 170-171.5° | |
| MSDS | Chinese USA | Flash Point | 172.3±25.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of (E)-Guggulsterone(-)-(E)-Guggulsterone is the metabolite of Z-guggulsterone. Guggulsterone is an active constituent of guggulipid, an ayurvedic drug derived from Commiphora mukul. Guggulsterone has hypolipidaemic activity[1]. |
| Name | (E)-Guggulsterone |
|---|---|
| Synonym | More Synonyms |
| Description | (-)-(E)-Guggulsterone is the metabolite of Z-guggulsterone. Guggulsterone is an active constituent of guggulipid, an ayurvedic drug derived from Commiphora mukul. Guggulsterone has hypolipidaemic activity[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 463.3±45.0 °C at 760 mmHg |
| Melting Point | 170-171.5° |
| Molecular Formula | C21H28O2 |
| Molecular Weight | 312.446 |
| Flash Point | 172.3±25.7 °C |
| Exact Mass | 312.208923 |
| PSA | 34.14000 |
| LogP | 3.65 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.557 |
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Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: insights into the antagonism of the hypolipidemic agent Z-guggulsterone.
Biochim. Biophys. Acta 1844(9) , 1684-93, (2014) Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative... |
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Guggulsterone attenuates cerulein-induced acute pancreatitis via inhibition of ERK and JNK activation.
Int. Immunopharmacol. 26 , 194-202, (2015) Guggulsterone (GS), a plant steroid and a compound found at high levels in Commiphora myrrha, exhibits anti-inflammatory, anti-cancer, and cholesterol-lowering effects. However, the potential of GS to... |
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CINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptor.
Mol. Pharmacol. 87(5) , 878-89, (2015) Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic sensors that enhance the detoxification and elimination of xenobiotics and endobiotics by modulating the expression ... |
| Z-guggulsterone |
| UNII:9B259YE66O |
| E-guggulsterone |
| Pregna-4,17-diene-3,16-dione, (17E)- |
| trans-Guggulsterone |
| Guggulsterone |
| (17E)-Pregna-4,17-diene-3,16-dione |
| Pregna-4,17(20)-diene-3,16-dione, (17E)- |
| (17E)-Pregna-4,17(20)-diene-3,16-dione |
| GUGGULSTERONE E |
| GS,TRANS |
| GUGGULESTERONE E |
| GUGGULSTERONE, (E)- |
| Z-Guggulsteron |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: (E)-Guggulsterone
- Price: ￥1808.0/5mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: (-)-(E)-Guggulsterone
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
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