Ac-Glu-Glu-Val-Val-Ala-Cys-pNA

Modify Date: 2024-01-18 17:14:51

Ac-Glu-Glu-Val-Val-Ala-Cys-pNA Structure
Ac-Glu-Glu-Val-Val-Ala-Cys-pNA structure
Common Name Ac-Glu-Glu-Val-Val-Ala-Cys-pNA
CAS Number 389868-12-6 Molecular Weight 810.872
Density 1.3±0.1 g/cm3 Boiling Point 1289.9±65.0 °C at 760 mmHg
Molecular Formula C34H50N8O13S Melting Point N/A
MSDS N/A Flash Point 733.9±34.3 °C

 Use of Ac-Glu-Glu-Val-Val-Ala-Cys-pNA


Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein[1].

 Names

Name N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-valyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-cysteinamide
Synonym More Synonyms

 Ac-Glu-Glu-Val-Val-Ala-Cys-pNA Biological Activity

Description Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein[1].
Related Catalog
References

[1]. Ede NJ, et al. Solid phase synthesis of peptide aldehyde protease inhibitors. Probing the proteolytic sites of hepatitis C virus polyprotein. J Pept Sci. 2000 Jan;6(1):11-8.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1289.9±65.0 °C at 760 mmHg
Molecular Formula C34H50N8O13S
Molecular Weight 810.872
Flash Point 733.9±34.3 °C
Exact Mass 810.321777
LogP 1.56
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.575

 Synonyms

L-Cysteinamide, N-acetyl-L-α-glutamyl-L-α-glutamyl-L-valyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-
N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-valyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-cysteinamide