389868-12-6

389868-12-6 structure

Name: Ac-Glu-Glu-Val-Val-Ala-Cys-pNA
Chemical Name: N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-valyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-cysteinamide
CAS Number: 389868-12-6
Molecular Formula: C₃₄H₅₀N₈O₁₃S
Molecular Weight: 810.872
Catalog: Signaling Pathways Metabolic Enzyme/Protease HCV Protease
Create Date: 2018-07-19 03:36:48
Modify Date: 2025-08-25 20:19:24
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein[1].

Name	N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-valyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-cysteinamide
Synonyms	L-Cysteinamide, N-acetyl-L-α-glutamyl-L-α-glutamyl-L-valyl-L-valyl-L-alanyl-N-(4-nitrophenyl)- N-Acetyl-L-α-glutamyl-L-α-glutamyl-L-valyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-cysteinamide

Description	Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease
References	[1]. Ede NJ, et al. Solid phase synthesis of peptide aldehyde protease inhibitors. Probing the proteolytic sites of hepatitis C virus polyprotein. J Pept Sci. 2000 Jan;6(1):11-8.