GW297361

Modify Date: 2024-01-23 10:27:10

GW297361 structure	Common Name	GW297361
	CAS Number	388627-21-2	Molecular Weight	372.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₂N₄O₃S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GW297361

GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively[1].

Name	GW297361

Description	GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Src Signaling Pathways >> Cell Cycle/DNA Damage >> CDK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	yeast Cdk1:20 nM (IC50) yeast Pho85:400 nM (IC50) human CDK2:1.9 nM (IC50) human CDK9:10 nM (IC50) human CDK1:30 nM (IC50) human CDK4:300 nM (IC50) VEGFR2:120 nM (IC50) SRC:930 nM (IC50)
In Vitro	GW297361 (20 μM; 15 min) 部分抑制细胞内的 Cdk1[1]。 Western Blot Analysis[1] Cell Line: YRP1 cells Concentration: 20 μM Incubation Time: 20 μM Result: An intermediate level of the Orc6 was converted to the faster-migrating isoform (lower:upper = 2:1).
References	[1]. Kung C, et al. Selective kinase inhibition by exploiting differential pathway sensitivity. Chem Biol. 2006 Apr;13(4):399-407.

Molecular Formula	C₁₆H₁₂N₄O₃S₂
Molecular Weight	372.42

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GW297361
Price: Check
Purity: 97.02%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

GW297361 suppliers

GW297361 price

GW297361

Use of GW297361

Names

GW297361 Biological Activity

Chemical & Physical Properties