Indole-4-boronic acid pinacol ester

Modify Date: 2024-01-11 10:33:32

Indole-4-boronic acid pinacol ester Structure
Indole-4-boronic acid pinacol ester structure
Common Name Indole-4-boronic acid pinacol ester
CAS Number 388116-27-6 Molecular Weight 243.109
Density 1.1±0.1 g/cm3 Boiling Point 396.0±15.0 °C at 760 mmHg
Molecular Formula C14H18BNO2 Melting Point 120-125ºC(lit.)
MSDS N/A Flash Point 193.3±20.4 °C

 Names

Name Indole-4-boronic acid, pinacol ester
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 396.0±15.0 °C at 760 mmHg
Melting Point 120-125ºC(lit.)
Molecular Formula C14H18BNO2
Molecular Weight 243.109
Flash Point 193.3±20.4 °C
Exact Mass 243.143066
PSA 34.25000
LogP 2.46710
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.562
Storage condition 2~8℃

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
HS Code 2933990090

 Synthetic Route

~99%

Indole-4-boronic acid pinacol ester Structure

Indole-4-boroni...

CAS#:388116-27-6

Literature: LOCUS PHARMACEUTICALS, INC. Patent: WO2008/8059 A1, 2008 ; Location in patent: Page/Page column 81-82 ;

~79%

Indole-4-boronic acid pinacol ester Structure

Indole-4-boroni...

CAS#:388116-27-6

Literature: GENENTECH, INC.; SUMITOMO CHEMICAL COMPANY, LIMITED Patent: US2012/123122 A1, 2012 ; Location in patent: Page/Page column 13-14 ;

~66%

Indole-4-boronic acid pinacol ester Structure

Indole-4-boroni...

CAS#:388116-27-6

Literature: SUGEN, INC. Patent: WO2004/76412 A2, 2004 ; Location in patent: Page 96 ; WO 2004/076412 A2

~38%

Indole-4-boronic acid pinacol ester Structure

Indole-4-boroni...

CAS#:388116-27-6

Literature: Kelly, Martha; Lee, Younghee; Liu, Bin; Fujimoto, Ted; Freundlich, Joel; Dorsey, Bruce D.; Flynn, Gary A.; Husain, Arifa Patent: US2006/270686 A1, 2006 ; Location in patent: Page/Page column 49-50 ;

~%

Indole-4-boronic acid pinacol ester Structure

Indole-4-boroni...

CAS#:388116-27-6

Literature: Deodhar, Mandar; Black, David Stc.; Shiu-Hin Chan, Daniel; Kumar, Naresh Heterocycles, 2010 , vol. 80, # 2 p. 1267 - 1274

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Indole-4-boronic acid pinacol ester
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
1H-Indole, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-