Fuberidazole

Modify Date: 2025-08-24 19:58:16

Fuberidazole structure	Common Name	Fuberidazole
	CAS Number	3878-19-1	Molecular Weight	184.19
	Density	1.286g/cm3	Boiling Point	380.6ºC at 760 mmHg
	Molecular Formula	C₁₁H₈N₂O	Melting Point	310-312℃
	MSDS	Chinese USA	Flash Point	194.7ºC
	Symbol	GHS06, GHS08, GHS09	Signal Word	Danger

Use of Fuberidazole

Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea[1].

Name	fuberidazole
Synonym	More Synonyms

Description	Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
Target	B. cinerea[1]
In Vitro	Fuberidazole (FBZ) (10 μM) 在 CB8 (100 μM) 存在的情况下表现出 1.4 个单位的 pKa 偏移[1]。 Fuberidazole (10-200 μM; 72 h) 对灰霉病菌 (B. cinerea) 表现出增加的生长抑制率。与 CB7/CB8 结合的 Fuberidazole 对 B. cinerea 的生长至少是 Fuberidazole 单独抑制 3 倍[1]。
References	[1]. Saleh N, et al. Enhancement of in vitro fungicidal activity of fuberidazole to Botrytis cinerea by cucurbiturils. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 79: 301-309.

Density	1.286g/cm3
Boiling Point	380.6ºC at 760 mmHg
Melting Point	310-312℃
Molecular Formula	C₁₁H₈N₂O
Molecular Weight	184.19
Flash Point	194.7ºC
Exact Mass	184.06400
PSA	41.82000
LogP	2.82290
Index of Refraction	1.67

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD9010000

CHEMICAL NAME :: Benzimidazole, 2-(2-furyl)-

CAS REGISTRY NUMBER :: 3878-19-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C11-H8-N2-O

MOLECULAR WEIGHT :: 184.21

WISWESSER LINE NOTATION :: T56 BM DNJ C- BT5OJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 330 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 825 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 15,273,1972 *** REVIEWS *** TOXICOLOGY REVIEW MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 32,151,1975

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H302-H311-H317-H330-H351-H373-H410
Precautionary Statements	P260-P273-P280-P284-P304 + P340 + P310-P403 + P233
Target Organs	Heart
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn,N
Risk Phrases	R22:Harmful if swallowed. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
Safety Phrases	S22-S60-S61
RIDADR	2588
WGK Germany	3.0
RTECS	DD9010000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Fubridazole

EINECS 223-404-0

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2-(furan-2-yl)-benzimidazole

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Benzimidazole,2-(2-furyl)

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Voronite

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MFCD00055496

2-(2-furyl)benzimidazole

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Voronit

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