Fuberidazole

Modify Date: 2024-01-03 12:32:00

Fuberidazole structure	Common Name	Fuberidazole
	CAS Number	3878-19-1	Molecular Weight	184.19
	Density	1.286g/cm3	Boiling Point	380.6ºC at 760 mmHg
	Molecular Formula	C₁₁H₈N₂O	Melting Point	310-312℃
	MSDS	Chinese USA	Flash Point	194.7ºC
	Symbol	GHS06, GHS08, GHS09	Signal Word	Danger

Use of Fuberidazole

Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea[1].

Name	fuberidazole
Synonym	More Synonyms

Description	Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
Target	B. cinerea[1]
In Vitro	Fuberidazole (FBZ) (10 μM) 在 CB8 (100 μM) 存在的情况下表现出 1.4 个单位的 pKa 偏移[1]。 Fuberidazole (10-200 μM; 72 h) 对灰霉病菌 (B. cinerea) 表现出增加的生长抑制率。与 CB7/CB8 结合的 Fuberidazole 对 B. cinerea 的生长至少是 Fuberidazole 单独抑制 3 倍[1]。
References	[1]. Saleh N, et al. Enhancement of in vitro fungicidal activity of fuberidazole to Botrytis cinerea by cucurbiturils. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 79: 301-309.

Density	1.286g/cm3
Boiling Point	380.6ºC at 760 mmHg
Melting Point	310-312℃
Molecular Formula	C₁₁H₈N₂O
Molecular Weight	184.19
Flash Point	194.7ºC
Exact Mass	184.06400
PSA	41.82000
LogP	2.82290
Index of Refraction	1.67

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD9010000

CHEMICAL NAME :: Benzimidazole, 2-(2-furyl)-

CAS REGISTRY NUMBER :: 3878-19-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C11-H8-N2-O

MOLECULAR WEIGHT :: 184.21

WISWESSER LINE NOTATION :: T56 BM DNJ C- BT5OJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 330 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 825 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 15,273,1972 *** REVIEWS *** TOXICOLOGY REVIEW MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 32,151,1975

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H302-H311-H317-H330-H351-H373-H410
Precautionary Statements	P260-P273-P280-P284-P304 + P340 + P310-P403 + P233
Target Organs	Heart
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn,N
Risk Phrases	R22:Harmful if swallowed. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
Safety Phrases	S22-S60-S61
RIDADR	2588
WGK Germany	3.0
RTECS	DD9010000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors.

Bioorg. Med. Chem. Lett. 20 , 4038-44, (2010)

Inhibitors of methionine aminopeptidases (MetAPs) are treatment options for various pathological conditions. Several inhibitor classes have been described previously, but only few data on the subtype ...

Metal-mediated inhibition of Escherichia coli methionine aminopeptidase: structure-activity relationships and development of a novel scoring function for metal-ligand interactions.

J. Med. Chem. 49 , 511-22, (2006)

We report the discovery of thiabendazole as a potent inhibitor (K(i) = 0.4 microM) of Escherichia coli methionine aminopeptidase (ecMetAP) and the synthesis and pharmacological evaluation of thiabenda...

Quantitative Fusarium spp. and Microdochium spp. PCR assays to evaluate seed treatments for the control of Fusarium seedling blight of wheat.

J. Appl. Microbiol. 102(6) , 1645-53, (2007)

To develop sensitive quantitative PCR assays for the two groups of pathogens responsible for Fusarium seedling blight in wheat: Fusarium group (Fusarium culmorum and Fusarium graminearum) and Microdoc...

Fubridazole

EINECS 223-404-0

2-(2-Furanyl)-1H-benzimidazole

2-(furan-2-yl)-benzimidazole

2-(furan-2-yl)-1H-benzo[d]imidazole

Benzimidazole,2-(2-furyl)

2-(furan-2-yl)-1H-benzimidazole

Fuberidatol

2-(2'-furyl)-benzimidazole

Voronite

Fuberidazol

Furidazole

Furidazol

MFCD00055496

2-(2-furyl)benzimidazole

Fuberisazol

2-(furan-2-yl)-1H-1,3-benzimidazole

2-(2'-furyl)-1H-benzimidazole

Voronit

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Fuberidazole
Price: ￥958.0/250mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Fuberidazole
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(2-FURYL)BENZIMIDAZOLE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Fuberidazole suppliers

Price: ￥300/5 mg

Reference only. check more Fuberidazole price

Fuberidazole

Use of Fuberidazole

Names

Fuberidazole Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Customs

Articles10

Synonyms