Triptonide

Modify Date: 2024-01-02 03:07:36

Triptonide structure	Common Name	Triptonide
	CAS Number	38647-11-9	Molecular Weight	358.385
	Density	1.5±0.1 g/cm3	Boiling Point	581.1±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₂O₆	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	257.8±30.2 °C
	Symbol	GHS06, GHS08	Signal Word	Danger

Use of Triptonide

Triptonide(NSC 165677; PG 492), extracted from Tripterygium wilfordii Hook, inhibited the proliferation of mouse splenocytes induced by suboptimal concentration of concanavalin A or lipopolysaccharide at concentrations of 0.02, 0.1, and 0.5 mg/ml.

Name	Triptonide
Synonym	More Synonyms

Description	Triptonide(NSC 165677; PG 492), extracted from Tripterygium wilfordii Hook, inhibited the proliferation of mouse splenocytes induced by suboptimal concentration of concanavalin A or lipopolysaccharide at concentrations of 0.02, 0.1, and 0.5 mg/ml.
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> β-catenin Signaling Pathways >> Stem Cell/Wnt >> Wnt Research Areas >> Others Natural Products >> Terpenoids and Glycosides
References	[1]. Wu YW, Jiang YY, Xiao TX, Zhang HL.Determination of triptonide by cloud point extraction combined with MEKC.J Sep Sci. 2008 Mar;31(5):865-71. [2]. Yao J, Zhang L, Zhao X, Hu L, Jiang Z.Simultaneous determination of triptolide, wilforlide A and triptonide in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.Biol Pharm Bull. 2006 Jul;29(7):1483-6. [3]. Wang Z, Wen J, Xing J, Guo D.Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography.Biomed Chromatogr. 2005 Jan;19(1):60-2. [4]. Wang L, Ye W, Hui L, Liu X, Guo Y.[Male contraception of triptonide and its function mechanism].Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2000 Jun;22(3):223-6. [5]. Corson, Timothy W.; Cavga, Hueseyin; Aberle, Nicholas; Crews, Craig M. Triptolide Directly Inhibits dCTP Pyrophosphatase. ChemBioChem (2011), 12(11), 1767-1773.

Description

Related Catalog

Signaling Pathways >> Stem Cell/Wnt >> β-catenin

Signaling Pathways >> Stem Cell/Wnt >> Wnt

Research Areas >> Others

Natural Products >> Terpenoids and Glycosides

References

[1]. Wu YW, Jiang YY, Xiao TX, Zhang HL.Determination of triptonide by cloud point extraction combined with MEKC.J Sep Sci. 2008 Mar;31(5):865-71.

[2]. Yao J, Zhang L, Zhao X, Hu L, Jiang Z.Simultaneous determination of triptolide, wilforlide A and triptonide in human plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.Biol Pharm Bull. 2006 Jul;29(7):1483-6.

[3]. Wang Z, Wen J, Xing J, Guo D.Determination of triptolide and triptonide in human plasma by high-performance liquid chromatography.Biomed Chromatogr. 2005 Jan;19(1):60-2.

[4]. Wang L, Ye W, Hui L, Liu X, Guo Y.[Male contraception of triptonide and its function mechanism].Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2000 Jun;22(3):223-6.

[5]. Corson, Timothy W.; Cavga, Hueseyin; Aberle, Nicholas; Crews, Craig M. Triptolide Directly Inhibits dCTP Pyrophosphatase. ChemBioChem (2011), 12(11), 1767-1773.

Density	1.5±0.1 g/cm3
Boiling Point	581.1±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂O₆
Molecular Weight	358.385
Flash Point	257.8±30.2 °C
Exact Mass	358.141632
PSA	80.96000
LogP	1.49
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.638
Storage condition	2-8°C

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H300 + H330-H361f
Precautionary Statements	P201-P260-P284-P301 + P310 + P330-P304 + P340 + P310-P403 + P233
Hazard Codes	T+
RIDADR	2811.0
Hazard Class	6.1

Precursor 5
CAS#:38748-32-2 Triptolide CAS#:144539-79-7 Triptolide CAS#:74654-69-6 (1R,2S,4aS,10aR... CAS#:74666-21-0 (4bS,8aR)-8-((b...
CAS#:74709-24-3 7β,14,19-trihyd...
DownStream 2
CAS#:144539-79-7 Triptolide CAS#:38748-32-2 Triptolide

l-triptonide

Triptolide,14-deoxy-14-oxo

Triptonide

(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione

Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione, 3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-

14-Deoxy-14-oxotriptolide

(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-8b-methyl-6a-(propan-2-yl)-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Triptonide
Price: ￥1088.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Triptolide,14-deoxy-14-oxo
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: Triptonide
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFUCHEM--38647-11-9--High purity Triptonide factory price
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

Get all suppliers and price by the below link:

Triptonide suppliers

Price: ￥1092/25mg

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Triptonide

Use of Triptonide

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Triptonide Biological Activity

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