Coumarin VI

Modify Date: 2024-01-03 19:24:44

Coumarin VI Structure
Coumarin VI structure
Common Name Coumarin VI
CAS Number 38215-36-0 Molecular Weight 350.43400
Density 1.311 g/cm3 Boiling Point 570.1ºC at 760 mmHg
Molecular Formula C20H18N2O2S Melting Point 208-210 °C(lit.)
MSDS Chinese USA Flash Point 298.6ºC

 Use of Coumarin VI


Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems[1].

 Names

Name coumarin 6
Synonym More Synonyms

 Coumarin VI Biological Activity

Description Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems[1].
Related Catalog
References

[1]. Elizebeth Purr, et al. Preparation of PLGA Nanoparticles Encapsulated with Fluorescent Probe Coumarin-6. bioRxiv preprint first posted online Apr. 23, 2019.

 Chemical & Physical Properties

Density 1.311 g/cm3
Boiling Point 570.1ºC at 760 mmHg
Melting Point 208-210 °C(lit.)
Molecular Formula C20H18N2O2S
Molecular Weight 350.43400
Flash Point 298.6ºC
Exact Mass 350.10900
PSA 74.58000
LogP 4.91590
Index of Refraction 1.69
Stability Stable. Incompatible with strong oxidizing agents.
Water Solubility NEGLIGIBLE

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22;R36/37/38
Safety Phrases S22-S24/25-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2934999090

 Synthetic Route

~80%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Lee, Seokjoon; Sivakumar, Krishnamoorthy; Shin, Woon-Seob; Xie, Fang; Wang, Qian Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4596 - 4599

~48%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Min, Minsik; Kim, Bomi; Hong, Sungwoo Organic and Biomolecular Chemistry, 2012 , vol. 10, # 13 p. 2692 - 2698

~72%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Mashraqui, Sabir H.; Vashi, Dhaval; Mistry, Hitesh D. Synthetic Communications, 2004 , vol. 34, # 17 p. 3129 - 3134

~58%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Zhou, Shihai; Jia, Jianhong; Gao, JianRong; Han, Liang; Li, Yujin; Sheng, Weijian Dyes and Pigments, 2010 , vol. 86, # 2 p. 123 - 128

~%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Ezeh, Vivian C.; Harrop, Todd C. Inorganic Chemistry, 2013 , vol. 52, # 5 p. 2323 - 2334

~%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Ezeh, Vivian C.; Harrop, Todd C. Inorganic Chemistry, 2013 , vol. 52, # 5 p. 2323 - 2334

~%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Li, Junbo; Zeng, Yang; Hu, Qihui; Yu, Xianglin; Guo, Jia; Pan, Zhiquan Dalton Transactions, 2012 , vol. 41, # 13 p. 3623 - 3626

~%

Coumarin VI Structure

Coumarin VI

CAS#:38215-36-0

Literature: Li, Junbo; Zeng, Yang; Hu, Qihui; Yu, Xianglin; Guo, Jia; Pan, Zhiquan Dalton Transactions, 2012 , vol. 41, # 13 p. 3623 - 3626

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

Coumarin 6,laser grade
EINECS 253-830-2
3-(2-Benzothiazolyl)-N,N-diethylumbelliferylamine (3-(2-Benzothiazolyl)-7-(diethylamino)coumarin
coumarin-540
3-(1,3-benzothiazol-2-yl)-7-(diethylamino)chromen-2-one
3-(benzo[d]thiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
MFCD00041869
3-(2-Benzothiazolyl)-7-(diethylamino)coumarin
3-(2-benzothiazolyl)-7-(diethylamino)-2H-1-benzopyran-2-one
3-benzothiazol-2-yl-7-(diethylamino)chromen-2-one
3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
3-(Benzothiazo-2-yl)-7-(diethylamino)-2H-chromen-2-one
2H-1-Benzopyran-2-one,3-(2-benzothiazolyl)-7-(diethylamino)