MMV-667492

Modify Date: 2024-01-17 17:58:49

MMV-667492 Structure
MMV-667492 structure
Common Name MMV-667492
CAS Number 380877-02-1 Molecular Weight 313.351
Density 1.4±0.1 g/cm3 Boiling Point 486.5±45.0 °C at 760 mmHg
Molecular Formula C17H19N3O3 Melting Point N/A
MSDS N/A Flash Point 248.0±28.7 °C

 Use of MMV-667492


MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM; exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787; a novel antimetastatic agent for the treatment of metastatic osteosarcoma.

 Names

Name 2-(Cyclohexylamino)-3-[methyl(nitroso)amino]-1,4-naphthoquinone
Synonym More Synonyms

 MMV-667492 Biological Activity

Description MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM; exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787; a novel antimetastatic agent for the treatment of metastatic osteosarcoma.
References References 1. Çelik H, et al. Mol Cancer Ther. 2015 Nov;14(11):2497-507. View Related Products by Target Ezrin

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 486.5±45.0 °C at 760 mmHg
Molecular Formula C17H19N3O3
Molecular Weight 313.351
Flash Point 248.0±28.7 °C
Exact Mass 313.142639
LogP 2.80
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.661

 Synonyms

1,4-Naphthalenedione, 2-(cyclohexylamino)-3-(methylnitrosoamino)-
2-(Cyclohexylamino)-3-[methyl(nitroso)amino]-1,4-naphthoquinone
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