MMV-667492

Names

[ Name ]:
MMV-667492

[Synonym ]:
1,4-Naphthalenedione, 2-(cyclohexylamino)-3-(methylnitrosoamino)-
2-(Cyclohexylamino)-3-[methyl(nitroso)amino]-1,4-naphthoquinone

Biological Activity

[Description]:

MMV-667492 (MMV 667492, MMV667492) is a novel potent Ezrin inhibitor with Kd of 29.4 nM; exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787; a novel antimetastatic agent for the treatment of metastatic osteosarcoma.

[References]

References 1. Çelik H, et al. Mol Cancer Ther. 2015 Nov;14(11):2497-507. View Related Products by Target Ezrin

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
486.5±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₉N₃O₃

[ Molecular Weight ]:
313.351

[ Flash Point ]:
248.0±28.7 °C

[ Exact Mass ]:
313.142639

[ LogP ]:
2.80

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.661

Related Compounds

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